Human skin optical property modifications upon optical clearing agents estimated from spatially-resolved tissue optical spectroscopy
Abstract
Optical clearing agents’ impact on skin optical properties (OP) was investigated using spatially – resolved bimodal spectroscopy and inverse Monte Carlo modelling. Optical spectra were obtained on an original hybrid model made of ex vivo human skin as a top layer and of agarose and porphyrin based – nanoparticles as a bottom layer. First results are given in terms of estimated absorption and scattering coefficients of skin layer before and after OCA application.