Lentiviral Transduction of CD34+ Cells Induces Genome-Wide Epigenetic Modifications

Yoshiaki Yamagata (1) , Véronique Parietti (1) , Daniel Stockholm (1) , Guillaume Corre (1) , Catherine Poinsignon (1) , Nizar Touleimat (2) , Damien Delafoy (2) , Céline Besse (2) , Jorg J. Tost (2) , Anne Galy (3) , András Paldi (1)

1 IMBI - Immunologie moléculaire et biothérapies innovantes
2 CNG - Centre National de Génotypage
3 Généthon

Keywords: Lentiviral vectors; Hematopoietic stem cells

Domains: Life Sciences [q-bio]; Cellular Biology; Life Sciences [q-bio]; Biotechnology; Life Sciences [q-bio]; Biochemistry, Molecular Biology; Life Sciences [q-bio]; Quantitative Methods [q-bio.QM]; Life Sciences [q-bio]; Genetics; Life Sciences [q-bio]; Immunology

Yoshiaki Yamagata, Véronique Parietti, Daniel Stockholm, Guillaume Corre, Catherine Poinsignon, et al.. Lentiviral Transduction of CD34+ Cells Induces Genome-Wide Epigenetic Modifications. PLoS ONE, 2012, 7 (11), pp.e48943. ⟨10.1371/journal.pone.0048943⟩. ⟨hal-02177572⟩