K. Kohno, H. Izumi, T. Uchiumi, M. Ashizuka, and M. Kuwano, The pleiotropic functions of the Y-box-binding protein, YB-1, Bioessays, vol.25, pp.691-698, 2003.

I. A. Eliseeva, E. R. Kim, S. G. Guryanov, L. P. Ovchinnikov, and D. N. Lyabin, Y-box-binding protein 1 (YB-1) and its functions, Biochemistry (Mosc), vol.76, pp.1402-1433, 2011.

D. N. Lyabin, I. A. Eliseeva, and L. P. Ovchinnikov, YB-1 protein: functions and regulation, Wiley Interdiscip Rev. RNA, vol.5, pp.95-110, 2014.

Z. H. Lu, J. T. Books, and T. J. Ley, YB-1 is important for late-stage embryonic development, optimal cellular stress responses, and the prevention of premature senescence, Mol. Cell. Biol, vol.25, pp.4625-4637, 2005.

W. J. Wei, S. R. Mu, M. Heiner, X. Fu, L. J. Cao et al., YB-1 binds to CAUC motifs and stimulates exon inclusion by enhancing the recruitment of U2AF to weak polypyrimidine tracts, Nucleic Acids Res, vol.40, pp.8622-8636, 2012.

W. B. Minich, I. P. Maidebura, and L. P. Ovchinnikov, Purification and characterization of the major 50-kDa repressor protein from cytoplasmic mRNP of rabbit reticulocytes, Eur. J. Biochem, vol.212, pp.633-638, 1993.

C. P. Kloks, C. A. Spronk, E. Lasonder, A. Hoffmann, G. W. Vuister et al., The solution structure and DNA-binding properties of the cold-shock domain of the human Y-box protein YB-1, J. Mol. Biol, vol.316, pp.317-326, 2002.

A. P. Wolffe, Structural and functional properties of the evolutionarily ancient Y-box family of nucleic acid binding proteins, Bioessays, vol.16, pp.245-251, 1994.

M. P. Nekrasov, M. P. Ivshina, K. G. Chernov, E. A. Kovrigina, V. M. Evdokimova et al., The mRNA-binding protein YB-1 (p50) prevents association of the eukaryotic initiation factor eIF4G with mRNA and inhibits protein synthesis at the initiation stage, J. Biol. Chem, vol.278, pp.13936-13943, 2003.

M. A. Skabkin, O. I. Kiselyova, K. G. Chernov, A. V. Sorokin, E. V. Dubrovin et al., Structural organization of mRNA complexes with major core mRNP protein YB-1, Nucleic Acids Res, vol.32, pp.5621-5635, 2004.

V. M. Evdokimova, E. A. Kovrigina, D. V. Nashchekin, E. K. Davydova, J. W. Hershey et al., The major core protein of messenger ribonucleoprotein particles (p50) promotes initiation of protein biosynthesis in vitro, J. Biol. Chem, vol.273, pp.3574-3581, 1998.

W. B. Minich and L. P. Ovchinnikov, Role of cytoplasmic mRNP proteins in translation, Biochimie, vol.74, pp.477-483, 1992.

V. Evdokimova, P. Ruzanov, M. S. Anglesio, A. V. Sorokin, L. P. Ovchinnikov et al., Akt-mediated YB-1 phosphorylation activates translation of silent mRNA species, Mol. Cell. Biology, vol.26, pp.277-292, 2006.

K. Matsumoto, F. Meric, and A. P. Wolffe, Translational repression dependent on the interaction of the Xenopus Y-box protein FRGY2 with mRNA. Role of the cold shock domain, tail domain, and selective RNA sequence recognition, J. Biol. Chem, vol.271, pp.22706-22712, 1996.

S. P. Somasekharan, N. Stoynov, B. Rotblat, G. Leprivier, J. D. Galpin et al., Identification and quantification of newly synthesized proteins translationally regulated by YB-1 using a novel Click-SILAC approach, J. Proteomics, vol.77, pp.1-10, 2012.

O. V. Skabkina, D. N. Lyabin, M. A. Skabkin, and L. P. Ovchinnikov, YB-1 autoregulates translation of its own mRNA at or prior to the step of 40S ribosomal subunit joining, Mol. Cell Biol, vol.25, pp.3317-3323, 2005.

B. Schwanhausser, D. Busse, N. Li, G. Dittmar, J. Schuchhardt et al., Global quantification of mammalian gene expression control, Nature, vol.473, pp.337-342, 2011.

D. A. Jackson, A. Pombo, and F. Iborra, The balance sheet for transcription: an analysis of nuclear RNA metabolism in mammalian cells, FASEB J, vol.14, pp.242-254, 2000.

Y. Arava, Y. Wang, J. D. Storey, C. L. Liu, P. O. Brown et al., Genome-wide analysis of mRNA translation profiles in Saccharomyces cerevisiae, Proc. Natl. Acad. Sci. U.S.A, vol.100, pp.3889-3894, 2003.

E. Stickeler, S. D. Fraser, A. Honig, A. L. Chen, S. M. Berget et al., The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4, EMBO J, vol.20, pp.3821-3830, 2001.

D. Ray, H. Kazan, E. T. Chan, L. Castillo, S. Chaudhry et al., Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins, Nat. Biotechnol, vol.27, pp.667-670, 2009.

D. Ray, H. Kazan, K. B. Cook, M. T. Weirauch, H. S. Najafabadi et al., A compendium of RNA-binding motifs for decoding gene regulation, Nature, vol.499, pp.172-177, 2013.

A. M. El-naggar, C. J. Veinotte, H. Cheng, T. G. Grunewald, G. L. Negri et al., Translational Activation of HIF1alpha by YB-1, 2015.

, Promotes Sarcoma Metastasis. Cancer Cell, vol.27, pp.682-697

W. H. Hudson and E. A. Ortlund, The structure, function and evolution of proteins that bind DNA and RNA, Nat. Rev. Mol. Cell Biol, vol.15, pp.749-760, 2014.

R. C. Bargou, K. Jurchott, C. Wagener, S. Bergmann, S. Metzner et al., Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression, Nat. Med, vol.3, pp.447-450, 1997.

T. Ohga, K. Koike, M. Ono, Y. Makino, Y. Itagaki et al., Role of the human Y box-binding protein YB-1 in cellular sensitivity to the DNA-damaging agents cisplatin, mitomycin C, and ultraviolet light, Cancer Res, vol.56, pp.4224-4228, 1996.

A. V. Sorokin, A. A. Selyutina, M. A. Skabkin, S. G. Guryanov, I. V. Nazimov et al., Proteasome-mediated cleavage of the Y-box-binding protein 1 is linked to DNA-damage stress response, EMBO J, vol.24, pp.3602-3612, 2005.

K. Higashi, Y. Inagaki, K. Fujimori, A. Nakao, H. Kaneko et al., Interferon-gamma interferes with transforming growth factor-beta signaling through direct interaction of YB-1 with Smad3, J. Biol. Chem, vol.278, pp.43470-43479, 2003.

M. Dutertre, G. Sanchez, M. C. De-cian, J. Barbier, E. Dardenne et al., Cotranscriptional exon skipping in the genotoxic stress response, Nat. Struc. Mol. Biol, vol.17, pp.1358-1366, 2010.

K. Shibao, H. Takano, Y. Nakayama, K. Okazaki, N. Nagata et al., Enhanced coexpression of YB-1 and DNA topoisomerase II alpha genes in human colorectal carcinomas, Int. J. Cancer, vol.83, pp.732-737, 1999.

T. Ohga, T. Uchiumi, Y. Makino, K. Koike, M. Wada et al., Direct involvement of the Y-box binding protein YB-1 in genotoxic stress-induced activation of the human multidrug resistance 1 gene, J. Biol. Chem, vol.273, pp.5997-6000, 1998.

S. L. Hasegawa, P. W. Doetsch, K. K. Hamilton, A. M. Martin, S. A. Okenquist et al., DNA binding properties of YB-1 and dbpA: binding to double-stranded, single-stranded, and abasic site containing DNAs, Nucleic Acids Res, vol.19, pp.4915-4920, 1991.

O. A. Zasedateleva, A. S. Krylov, D. V. Prokopenko, M. A. Skabkin, L. P. Ovchinnikov et al., Specificity of mammalian Y-box binding protein p50 in interaction with ss and ds DNA analyzed with generic oligonucleotide microchip, J. Mol. Biol, vol.324, pp.73-87, 2002.

M. Janz, N. Harbeck, P. Dettmar, U. Berger, A. Schmidt et al., Y-box factor YB-1 predicts drug resistance and patient outcome in breast cancer independent of clinically relevant tumor biologic factors HER2, uPA and PAI-1, Int. J. Cancer, vol.97, pp.278-282, 2002.

A. Lasham, C. G. Print, A. G. Woolley, S. E. Dunn, and A. W. Braithwaite, YB-1: oncoprotein, prognostic marker and therapeutic target?, Biochem. J, vol.449, pp.11-23, 2013.

T. Ise, G. Nagatani, T. Imamura, K. Kato, H. Takano et al., Transcription factor Y-box binding protein 1 binds preferentially to cisplatin-modified DNA and interacts with proliferating cell nuclear antigen, Cancer Res, vol.59, pp.342-346, 1999.

E. R. Kim, A. A. Selyutina, I. A. Buldakov, V. Evdokimova, L. P. Ovchinnikov et al., The proteolytic YB-1 fragment interacts with DNA repair machinery and enhances survival during DNA damaging stress, Cell Cycle, vol.12, pp.3791-3803, 2013.

G. H. Macdonald, Y. Itoh-lindstrom, and J. P. Ting, The transcriptional regulatory protein, YB-1, promotes single-stranded regions in the DRA promoter, J. Biol. Chem, vol.270, pp.3527-3533, 1995.

H. Izumi, T. Imamura, G. Nagatani, T. Ise, T. Murakami et al., Y box-binding protein-1 binds preferentially to single-stranded nucleic acids and exhibits 3 ->5 exonuclease activity, Nucleic Acids Res, vol.29, pp.1200-1207, 2001.

D. Dolfini and R. Mantovani, Targeting the Y/CCAAT box in cancer: YB-1 (YBX1) or NF-Y?, Cell Death Differ, vol.20, pp.676-685, 2013.

L. Hamon, D. Pastre, P. Dupaigne, C. Le-breton, E. Le-cam et al., High-resolution AFM imaging of single-stranded DNA-binding (SSB) protein-DNA complexes, Nucleic Acids Res, vol.35, p.58, 2007.

S. G. Guryanov, O. M. Selivanova, A. D. Nikulin, G. A. Enin, B. S. Melnik et al., Formation of amyloid-like fibrils by Y-box binding protein 1 (YB-1) is mediated by its cold shock domain and modulated by disordered terminal domains, PloS one, vol.7, p.36969, 2012.

S. G. Guryanov, V. V. Filimonov, A. A. Timchenko, B. S. Melnik, H. Kihara et al., The major mRNP protein YB-1: structural and association properties in solution, Biochim. Biophys. Acta, vol.1834, pp.559-567, 2013.

J. L. Nitiss, E. Soans, A. Rogojina, A. Seth, and M. Mishina, Topoisomerase assays, Curr. Protoc. Pharmacol, 2012.

S. R. Tafuri and A. P. Wolffe, DNA binding, multimerization, and transcription stimulation by the Xenopus Y box proteins in vitro, New Biol, vol.4, pp.349-359, 1992.

M. T. Murray, Nucleic acid-binding properties of the Xenopus oocyte Y box protein mRNP3+4, Biochemistry, vol.33, pp.13910-13917, 1994.

S. L. Hunt, J. J. Hsuan, N. Totty, and R. J. Jackson, ) unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNA, Genes Dev, vol.13, pp.437-448, 1999.

A. G. Baltz, M. Munschauer, B. Schwanhausser, A. Vasile, Y. Murakawa et al., The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts, Mol. Cell, vol.46, pp.674-690, 2012.

S. Gallois-montbrun, B. Kramer, C. M. Swanson, H. Byers, S. Lynham et al., Antiviral protein APOBEC3G localizes to ribonucleoprotein complexes found in P bodies and stress granules, J Virol, vol.81, pp.2165-2178, 2007.

O. Bounedjah, B. Desforges, T. D. Wu, C. Pioche-durieu, S. Marco et al., Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules, Nucleic Acids Res, vol.42, pp.8678-8691, 2014.

J. R. Buchan and R. Parker, Eukaryotic stress granules: the ins and outs of translation, Mol. Cell, vol.36, pp.932-941, 2009.

H. Tourriere, K. Chebli, L. Zekri, B. Courselaud, J. M. Blanchard et al., The RasGAP-associated endoribonuclease G3BP assembles stress granules, J. Cell Biol, vol.160, pp.823-831, 2003.

P. Graumann, T. M. Wendrich, M. H. Weber, K. Schroder, and M. A. Marahiel, A family of cold shock proteins in Bacillus subtilis is essential for cellular growth and for efficient protein synthesis at optimal and low temperatures, Mol. Microbiol, vol.25, pp.741-756, 1997.

W. Jiang, Y. Hou, and M. Inouye, CspA, the major cold-shock protein of Escherichia coli, is an RNA chaperone, J. Biol. Chem, vol.272, pp.196-202, 1997.

F. Mayr, A. Schutz, N. Doge, and U. Heinemann, The Lin28 cold-shock domain remodels pre-let-7 microRNA, Nucleic Acids Res, vol.40, pp.7492-7506, 2012.

V. Evdokimova, P. Ruzanov, H. Imataka, B. Raught, Y. Svitkin et al., The major mRNA-associated protein YB-1 is a potent 5 cap-dependent mRNA stabilizer, EMBO J, vol.20, pp.5491-5502, 2001.

D. A. Wacker, D. D. Ruhl, E. H. Balagamwala, K. M. Hope, T. Zhang et al., The DNA binding and catalytic domains of poly(ADP-ribose) polymerase 1 cooperate in the regulation of chromatin structure and transcription, Mol. Cell Biol, vol.27, pp.7475-7485, 2007.

M. L. Meyer-ficca, J. D. Lonchar, M. Ihara, M. L. Meistrich, C. A. Austin et al., Poly(ADP-ribose) polymerases PARP1 and PARP2 modulate topoisomerase II beta (TOP2B) function during chromatin condensation in mouse spermiogenesis, Biol Reprod, vol.84, pp.900-909, 2011.

B. M. Lunde, C. Moore, and G. Varani, RNA-binding proteins: modular design for efficient function, Nat. Rev. Mol. Cell Biol, vol.8, pp.479-490, 2007.

R. C. Deo, J. B. Bonanno, N. Sonenberg, and S. K. Burley, Recognition of polyadenylate RNA by the poly (A)-binding protein, Cell, vol.98, pp.835-845, 1999.

U. P. Guenther, L. E. Yandek, C. N. Niland, F. E. Campbell, D. Anderson et al., Hidden specificity in an apparently nonspecific RNA-binding protein, Nature, vol.502, pp.385-388, 2013.

R. Singh and J. Valcarcel, Building specificity with nonspecific RNA-binding proteins, Nat. Struct. Mol. Biol, vol.12, pp.645-653, 2005.

A. Borodavka, R. Tuma, and P. G. Stockley, Evidence that viral RNAs have evolved for efficient, two-stage packaging, Proc. Natl. Acad. Sci. U.S.A, vol.109, pp.15769-15774, 2012.

A. Castello, B. Fischer, K. Eichelbaum, R. Horos, B. M. Beckmann et al., Insights into RNA biology from an atlas of mammalian mRNA-binding proteins, Cell, vol.149, pp.1393-1406, 2012.

J. C. Schwartz, X. Wang, E. R. Podell, and T. R. Cech, RNA seeds higher-order assembly of FUS protein, Cell Rep, vol.5, pp.918-925, 2013.

M. Kato, T. W. Han, S. Xie, K. Shi, X. Du et al., Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels, Cell, vol.149, pp.753-767, 2012.

G. Toba and K. White, The third RNA recognition motif of Drosophila ELAV protein has a role in multimerization, Nucleic Acids Res, vol.36, pp.1390-1399, 2008.

P. Kundu, M. R. Fabian, N. Sonenberg, S. N. Bhattacharyya, and W. Filipowicz, HuR protein attenuates miRNA-mediated repression by promoting miRISC dissociation from the target RNA, Nucleic Acids Res, vol.40, pp.5088-5100, 2012.

E. J. Fialcowitz-white, B. Y. Brewer, J. D. Ballin, C. D. Willis, E. A. Toth et al., Specific protein domains mediate cooperative assembly of HuR oligomers on AU-rich mRNA-destabilizing sequences, J. Biol. Chem, vol.282, pp.20948-20959, 2007.

A. Devaux, L. J. Colegrove-otero, and N. Standart, Xenopus ElrB, but not ElrA, binds RNA as an oligomer: possible role of the linker, FEBS lett, vol.580, pp.4947-4952, 2006.

M. Ernoult-lange, S. Baconnais, M. Harper, N. Minshall, S. Souquere et al., Multiple binding of repressed mRNAs by the P-body protein Rck/p54, RNA, vol.18, pp.1702-1715, 2012.
URL : https://hal.archives-ouvertes.fr/hal-01004128

D. Dolfini and R. Mantovani, YB-1 (YBX1) does not bind to Y/CCAAT boxes in vivo, Oncogene, vol.32, pp.4189-4190, 2013.

X. Li and W. D. Heyer, Homologous recombination in DNA repair and DNA damage tolerance, Cell Res, vol.18, pp.99-113, 2008.