NMR assignment of PN2-3, a tubulin interaction subdomain of the CPAP protein

Marie-Jeanne Clément (1) , Philippe Savarin (1) , Jérôme Coutant (1) , Flavio Toma (1) , Patrick Curmi (1)

1 SABNP - Structure et activité des biomolécules normales et pathologiques

We report the NMR assignment of the PN2-3 subdomain of the CPAP protein. It has been previously shown that this motif interacts with tubulin, inhibits microtubule nucleation from the centrosome and depolymerizes taxol-stabilized microtubules.

Keywords: NMR assignment; Microtubules; CPAP; Centrosome; Tubulin

Domains: Life Sciences [q-bio]

Marie-Jeanne Clément, Philippe Savarin, Jérôme Coutant, Flavio Toma, Patrick Curmi. NMR assignment of PN2-3, a tubulin interaction subdomain of the CPAP protein. Biomolecular NMR Assignments, 2008, 115, 2, pp.115-117. ⟨10.1007/s12104-008-9099-3⟩. ⟨hal-02295383⟩